Journal of Natural Products Vol. 51, No. 6, pp. 1075-1079, Nov-Dec 1988
Ann F. Vogelmann,
Jet Propulsion Laboratory, California Institute of Technology, Pasadena, California 91109
Jocelyn C. Turner & Paul G. Mahlberg.
Department of Biology, Indiana University, Bloomington, Indiana 47405
Keywords: Cannabis sativa, Cannabaceae, cannabinoids, seedling, adult
Cannabinoid ratios in Cannabis sativa were compared in developing seedlings and adult plants of different ages. Analyses were performed on primary and secondary leaves from seedling plants and 4- and 7. 5-cm leaves from adult plants. In seedlings of a drug strain, maximum cannabinoid levels were obtained in primary leaves at 120-122 h. Cannabichromene (CBC) was the dominant cannabinoid of young seedlings. The dominant cannabinoid of older plants, D9-terrahydrocannabinol (THC), was present in the least amount in all seedlings through age 120-122 h. By age 144-146 h, when other cannabinoid amounts were declining, THC was emerging as the major cannabinoid. This was attributed to increased levels of THC in secondary leaves in older seedlings. The cannabinoid profile of young seedlings differs significantly from that of adult plants, and the transition to the adult profile begins with the formation of secondary leaves.